Guest Editorial - The indispensable way

eFOODLab_International_03_2014

The indispensable way Derk Wilten commercial director of Synchron Lab Automation Derk Wilten on High Throughput Experimentation (HTE) Today, more than ever, product developers in research face a growing array of new challenges. Not only are product quality, health and safety (think of REACH) requirements increasingly stringent, but fierce competition is also forcing companies to develop new products in shorter time spans. Nevertheless, many products are still being developed in iterative optimization steps. i.e.; the results of one small experiment are the basis for a next small experiment. If the optimization path is reviewed in the end, one will discover that only a small part of the multi-dimensional parameter space has been explored. As a result, in such cases, developers are having a hard time being certain that their findings, with regards to product properties, quality, robustness and costs, are optimal. HTE techniques on the other hand enable product developers to study the complete parameter space in a fast, easy and accurate way. This is achieved by performing a broad automated screening followed by a fast, quantitative optimization of the recipe. Also, with HTE the use of statistical design of experiments (DoE) is crucial, resulting in developers obtaining Knowledge, making better decisions and de- creasing their time to market. In the 1990s High Throughput Techniques were developed in the life science and pharmaceutical research area. Then, with the advent of robots enabled for the handling of various materials, the industrial market followed suite. However, the reigning conservative attitude of the industrial market made for a slow adoption of HTE techniques. Today however HTE has been generally accepted as an extremely useful research tool within the industrial market. Because automated formulation does not make sense without automated screening, since this would only shift the rate determining step in the R&D process, focus has shifted towards development of HT analy- sis and screening techniques. Now it is becoming possible to perform your experiments completely within the HTE cycle; Design of Experiments in, Data out and all in between automated. So with the many challenges that lie ahead for product developers, HTE is now an indispensable research tool for the chemical industry. HTE is now an indispensable research tool for the chemical industry. In the foreseeable future also other industries such as the food industry will apply this new technology. The first projects are being started. And thankfully I am not the only person who thinks so. About Derk Wilten Synchron develops custom made laboratory automation solutions and is specialised in automated liquid handling. We deliver State of the Art liquid handling robotics with on-demand customized modules. Due to these modules, applications in all fields can be accomplished. Since 1986 Synchron has been developing special products and software in good relationships with customers, manufacturers and suppliers of laboratory instruments. Derk Wilten is the commercial director of Synchron Lab Automation and is a fourth generation entrepreneur from the Dutch family company Wilten, which exists since 1952. Wilten has been active on the market for laboratory instruments since its creation. Guest Editorial 3/14 ¤ eFOOD-Lab international 3


eFOODLab_International_03_2014
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